Acid Reflux Drugs Causing Widespread Iron Deficiency Anemia

As of August 2025, a growing number of people are suffering from iron deficiency anemia, often unaware of the underlying cause. The article profiles two individuals, Brigitte Siefken and Derek Roberts, who both experienced debilitating fatigue and other symptoms for years before finally receiving a diagnosis.

Brigitte, a 55-year-old finance assistant, had been taking proton pump inhibitors (PPIs) for chronic acid reflux for over 15 years. These medications, which are some of the most commonly prescribed drugs in the UK, can cause iron deficiency over long-term use by reducing stomach acid needed for iron absorption. Brigitte's iron levels were dangerously low, leading to symptoms like tiredness, brain fog, and hair loss.

Similarly, Derek Roberts, a 38-year-old social media manager, struggled with unexplained fatigue and anemia for three years before discovering he had undiagnosed coeliac disease. The autoimmune condition was damaging his gut and preventing proper nutrient absorption, including iron.

Experts warn that iron deficiency anemia is often overlooked, with many patients simply told they are "just tired" without proper testing. They emphasize the need for regular ferritin tests, especially for those on long-term PPI use or with gastrointestinal issues, to catch the condition early and prevent serious complications.