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Tempus AI Surges on Genomics Boost and AI Deployment
17 Nov
Summary
- Tempus AI's Q3 results beat expectations, with genomics revenue up ~27%
- AI deployment in clinical practice could drive strong long-term growth
- Adjusted EBITDA turned positive, but GAAP net loss due to costs

On November 5, 2025, Tempus AI, Inc. (NASDAQ:TEM) reported strong Q3 results, sending Wall Street sentiment soaring. The health-tech company, which applies artificial intelligence to clinical and molecular data, saw its genomics business deliver a standout performance.
Tempus' oncology test volumes jumped around 27%, while hereditary testing surged, pushing total genomics revenue to approximately $253 million. This "Ambry-boosted" genomics engine was the key driver behind the company's overall sales of $334 million. The Data/Services segment also grew, with Insights licensing leading the way, allowing Tempus to spread its fixed costs more widely and lift gross profit to around $210 million.
While Tempus' adjusted EBITDA turned positive, its GAAP net income remained in the red due to stock compensation, new Ambry amortization, and a $12 million debt-extinguishment hit. However, the market's reaction was not about demand, as management raised the full-year guidance, citing the durability of these growth levers.




