What is "Best Medicine" about?

"Best Medicine" is a new one-hour comedy series that follows Dr. Martin Best, a brilliant surgeon played by Josh Charles, who abruptly leaves his career in Boston to become the general practitioner in a quaint East Coast fishing village.

Who are the main characters in "Best Medicine"?

The main characters include Dr. Martin Best, played by Josh Charles, as well as school teacher Louisa Glasson (Abigail Spencer), Martin's aunt Joan (Annie Potts), his assistant Elaine Denton (Cree), and sheriff Mark Mylow (Josh Segarra).

What is Dr. Martin Best's relationship with the locals in the fishing village?

Despite Dr. Best's blunt and standoffish bedside manner, the quirky locals in the small town are determined to make him a beloved "Doc Martin" figure, much to his consternation.

Home / Arts and Entertainment / Brilliant Surgeon Leaves Boston for Quirky Fishing Village in "Best Medicine"

Brilliant Surgeon Leaves Boston for Quirky Fishing Village in "Best Medicine"

3 Nov

•

Summary

Josh Charles stars as Dr. Martin Best, a brilliant surgeon who leaves his career in Boston
Dr. Best becomes the general practitioner in a quaint East Coast fishing village
Locals try to make him a "homey favorite" despite his icy manner and standoffish replies

Brilliant Surgeon Leaves Boston for Quirky Fishing Village in "Best Medicine"

According to a news article published on November 3, 2025, the upcoming Fox comedy series "Best Medicine" will follow the story of Dr. Martin Best, played by Josh Charles. Dr. Best is a brilliant surgeon who unexpectedly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child.

However, the locals in this small community are determined to make Dr. Best a beloved "Doc Martin" figure, despite his icy manner and standoffish replies. From the local restaurant to the traditional town fair, the quirky residents seem intent on embracing the new doctor, even as his blunt bedside manner rubs them the wrong way.

What the locals don't know is that Dr. Best's terse demeanor actually masks a debilitating new phobia and deep-seated psychological issues that prevent him from experiencing true intimacy with anyone. The supporting cast includes Abigail Spencer, Annie Potts, Cree, and Josh Segarra. "Best Medicine" is set to premiere on Fox in January 2026.

Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.