Amnesiac Doctor Struggles to Reclaim Her Life in Hit Series 'Doc'

The medical drama 'Doc' has proven to be a big hit since premiering on Fox in September 2025. The series follows Dr. Amy Larson, the chief of internal medicine at a fictional Minneapolis hospital, who suffers a brain injury that wipes out the last 8 years of her memory.

Suddenly confronted with a teenage daughter, a failed marriage, and the trauma of a deceased child, Larson must work to rebuild her personal and professional life. The series is based on an Italian show that was itself inspired by the real-life case of Dr. Pierdante Piccioni, an Italian emergency room chief who lost 12 years of his memory after a car accident in 2013.

Acclaimed actress Molly Parker delivers a powerful, vulnerable performance as Larson, anchoring the show's emotional core. Viewers have been captivated by Larson's journey to reclaim her identity and reconnect with her loved ones, all while navigating the challenges of returning to her high-stakes medical career.

With the first season now streaming on Netflix ahead of the second season premiere, 'Doc' has proven to be a breakout hit, blending medical drama with deeply personal storylines. The series offers a unique and compelling exploration of memory loss and resilience, resonating with audiences who have been eagerly awaiting the next chapter in Larson's story.