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Colts' Undefeated Run Faces Stern Rams Test
28 Sep, 2025
Summary
- Colts 3-0, but missing key starters
- Rams' stout defense and creative offense led by Stafford
- Experts unanimously pick Rams to win

As of September 29th, 2025, the Indianapolis Colts are 3-0 this season, led by quarterback Daniel Jones and one of the league's most productive offenses. However, the Colts will be without a few key starters for this upcoming game.
On the other side, the Los Angeles Rams are 2-1, boasting a very stout defensive front and the creative offensive scheme of head coach Sean McVay. Veteran quarterback Matthew Stafford leads the Rams' attack.
Experts unanimously believe the Rams will emerge victorious in this matchup, as the Colts face their toughest test of the young season. Analysts cite the Rams' ability to contain Colts running back Jonathan Taylor and force Daniel Jones to beat them through the air as key factors in their prediction.
The Rams will be looking to bounce back after a heartbreaking loss to the Philadelphia Eagles the previous week. This game presents a significant challenge for the undefeated Colts, who will need to overcome the Rams' formidable defense to maintain their perfect start to the 2025 campaign.