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Louisville's Injury Crisis: Key Players Out for ACC Finale
21 Nov
Summary
- Louisville's star running back Isaac Brown remains out with injuries.
- Keyjuan Brown, Antonio Watts, and Miller Moss are sidelined or questionable.
- SMU's offense features QB Kevin Jennings and a strong defensive end Isaiah Smith.

The Louisville football program faces a critical ACC finale on the road against SMU in Dallas, significantly hampered by a string of key injuries. Star running back Isaac Brown remains unavailable, and his usual backup, Keyjuan Brown, has been ruled out. Linebacker Antonio Watts is also sidelined, with quarterback Miller Moss listed as questionable. These absences place immense pressure on the remaining Cardinals roster.
Despite Louisville's injury woes, SMU appears healthier, with most of their previously injured players removed from the report. The Mustangs are led by quarterback Kevin Jennings, who has demonstrated strong passing numbers despite dealing with an ankle injury that has limited his dual-threat capabilities. Defensively, SMU boasts playmakers like safety Ahmaad Moses and linebacker Brandon Miyazono, but defensive end Isaiah Smith stands out as an All-American candidate with a conference-leading 16.0 tackles for loss.
The matchup features a critical battle between Louisville's offensive tackles and SMU's formidable edge rushers, including Isaiah Smith. While Louisville's offense has struggled recently, their offensive tackles Trevonte Sylvester and Rasheed Miller have shown improvement. The Cardinals will also look to the surprising surge of third-string running back Keyjuan Brown, who has averaged 9.0 yards per carry over the last four games, to carry the load.




