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Turmeric Drug Lights Up Cancer Cells
16 Feb
Summary
- Turmeric's curcumin compound is engineered into a smart drug delivery system.
- The system precisely targets tumors, illuminating them for real-time monitoring.
- This innovation enhances drug efficacy while minimizing damage to healthy tissues.
Researchers at Maharaja Sayajirao University have pioneered a revolutionary cancer treatment utilizing curcumin, the active component in turmeric. This innovative approach employs a "smart" drug delivery system that precisely targets cancerous tumors. The engineered curcumin glows when aggregated within tumor tissue, acting as a visual guide for doctors to monitor treatment progress and tumor shrinkage in real-time.
The system, funded by the Anusandhan National Research Foundation, uses nanomicelles to carry chemotherapy drugs. These carriers are designed to remain stable in the bloodstream but release their payload exclusively in the acidic microenvironment characteristic of tumors. This targeted release enhances drug efficacy and drastically reduces collateral damage to healthy organs.
This theranostic platform, combining therapeutic action with diagnostic imaging, was developed by Prof Sonal Thakore and her team. Tests involving breast and liver cancer cell lines and animal models demonstrated significant improvements in treatment outcomes with minimal impact on critical organs. The use of biocompatible and naturally derived components suggests potential for safer and more affordable cancer care, with ongoing studies focused on clinical translation.
