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Trailblazer Leeman Reshaped Brain Signal Science
25 Feb
Summary
- Susan Leeman identified neuropeptides linked to chronic pain.
- She pursued science despite overt sexism in academia.
- Leeman discovered Substance P and neurotensin in the 1970s.

Susan E. Leeman, a pioneering neuroscientist whose discoveries reshaped understanding of brain chemical signaling, passed away at 95. She identified two crucial neuropeptides, Substance P and neurotensin, in the 1970s. Substance P was later linked to chronic pain syndromes and migraines.
Dr. Leeman's career began in the 1950s, a time of overt sexism in science. She earned her doctorate from Harvard in 1958 but faced significant discrimination, delaying her tenured academic position for 22 years.
Her research required dedication, even visits to slaughterhouses for tissue. Despite challenges, she secured professorships at UMass Medical School and Boston University, earning accolades including election to the National Academy of Sciences.
Leeman continued her scientific pursuits until nearly 90, leaving a legacy of perseverance and groundbreaking discoveries in neuroendocrinology.




