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Slime Mold Inspires Sugar Substitute Breakthrough
15 Jan
Summary
- Engineered bacteria create tagatose, a sweetener 92% as sweet as sugar.
- This new tagatose production method offers higher yields and is cost-effective.
- Tagatose offers potential benefits for blood sugar and oral health.

Researchers have developed a groundbreaking method for producing tagatose, a healthier sugar alternative, by harnessing the power of engineered bacteria and a unique enzyme found in slime mold. This novel process converts abundant glucose into tagatose with unprecedented efficiency, potentially making this low-calorie sweetener more accessible.
Traditionally, tagatose production has been costly and inefficient. The new technique utilizes genetically modified Escherichia coli bacteria, incorporating a slime mold enzyme to effectively reverse a natural metabolic pathway. This results in significantly higher yields, surpassing conventional manufacturing methods and paving the way for industrial scalability.
Beyond its use as a bulk sweetener that behaves like sugar in cooking and baking, tagatose offers potential health benefits. It has a minimal impact on blood glucose and insulin levels and may even inhibit harmful oral bacteria, positioning it as a promising alternative for consumers seeking healthier options without compromising taste or texture.



