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Nobel Laureates Honored for Immune Tolerance Breakthroughs
6 Oct
Summary
- Three scientists awarded 2025 Nobel Prize in Medicine
- Discoveries on peripheral immune tolerance lay foundation for new treatments
- Prize sum of 11 million Swedish crowns ($1.2 million)
On October 6, 2025, the Nobel Assembly at Karolinska Institutet in Stockholm, Sweden, announced the winners of the prestigious Nobel Prize in Physiology or Medicine. This year's laureates are Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi, who have been recognized for their "discoveries concerning peripheral immune tolerance."
The Nobel Committee praised the trio's work, stating that their findings have "laid the foundation for a new field of research and spurred the development of new treatments, for example for cancer and autoimmune diseases." The prize sum of 11 million Swedish crowns (approximately $1.2 million) will be awarded to the scientists, along with a gold medal presented by the Swedish king.
The Nobel Prizes, established through the will of Alfred Nobel, have been awarded annually since 1901 for outstanding contributions in science, literature, and peace. The medicine prize, which kicks off the annual Nobel celebrations, has recognized numerous groundbreaking discoveries over the decades, including the development of COVID-19 vaccines in recent years.
