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Home / Science / Microplastics Clog Arteries, Fueling Heart Disease Risk

Microplastics Clog Arteries, Fueling Heart Disease Risk

31 Dec, 2025

•

Summary

  • Microplastics dramatically increase arterial plaque in male mice.
  • Atherosclerosis risk is linked to microplastics, not just cholesterol.
  • Endothelial cells are most affected by microplastic exposure.
Microplastics Clog Arteries, Fueling Heart Disease Risk

A recent study indicates that microplastics may directly cause cardiovascular disease by significantly increasing arterial plaque. Researchers observed that male mice exposed to microplastics showed a dramatic rise in plaque accumulation in their arteries, a condition known as atherosclerosis.

The study further revealed that microplastics appear to activate genes within endothelial cells, which line blood vessels, leading to inflammation and plaque formation. This effect was also observed in cultured human endothelial cells, suggesting a direct cellular mechanism for the observed plaque buildup.

While the research highlights a concerning link between microplastics and heart disease, scientists emphasize the need for further investigation into the specific mechanisms and differences between sexes. Current advice for individuals focuses on reducing exposure through avoiding single-use plastics and certain food and water sources.

Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.
The UCR study found that microplastics significantly increase plaque accumulation in arteries, particularly in male mice, potentially leading to cardiovascular disease.
Atherosclerosis is the buildup of plaque in arteries. The study suggests microplastics may directly induce this buildup by affecting cells that line blood vessels.
While the study shows microplastics correlate with increased plaque, and plaque is linked to heart attacks and strokes, further research is needed to confirm a direct causal link in humans.

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