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Indian Scientists Create 'Placenta-on-Chip'

Summary

  • A lab-grown 'placenta-on-chip' platform was developed in India.
  • The chip mimics crucial placental functions like hormone production and nutrient transfer.
  • This technology aids research into pregnancy complications and drug safety.
Indian Scientists Create 'Placenta-on-Chip'

A novel 'placenta-on-chip' platform has been developed by scientists in India, offering a significant advancement in understanding pregnancy. This lab-grown system meticulously recreates critical functions of the human placenta, including hormone production, nutrient delivery, and waste removal. It effectively models the vital interface between mother and fetus, providing unprecedented insights into biological processes that sustain pregnancy.

The Indian platform demonstrates capabilities such as transporting glucose and removing waste, and it can even simulate conditions like gestational diabetes. This makes it a valuable tool for studying placental biology and pregnancy complications. Researchers anticipate it will aid in assessing how medicines cross the placental barrier and support the development of more predictive, human-relevant research models.

Designed for simplicity and scalability, this system is compatible with standard laboratory equipment, potentially increasing its adoption. The interdisciplinary collaboration between engineers and biomedical scientists was crucial for its success. This innovation aligns with global efforts to develop alternatives to animal experimentation in reproductive health research and could offer new insights into disorders like pre-eclampsia.

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