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Exercise Rewires Heart Nerves in Rats
27 Oct
Summary
- Ten weeks of exercise altered nerve clusters controlling rat hearts.
- Left stellate ganglia neurons doubled in size; right ones shrank.
- Study offers insights for treating heart rhythm and pain issues.

Scientists have discovered that regular exercise can significantly alter the nerve pathways that regulate heart function. A recent study conducted on rats revealed that a mere ten weeks of moderate aerobic activity led to substantial structural changes in the stellate ganglia, the nerve clusters responsible for automatic heart rate regulation.
The research highlighted notable differences between the left and right stellate ganglia. In trained rats, the right nerve bundle contained approximately four times more neurons than the left. Furthermore, neurons on the left nearly doubled in size, while those on the right experienced a slight reduction.
These findings suggest that exercise impacts the nervous system's control over the heart in a differentiated manner. While the experiment was performed on rats, scientists are hopeful that this research will pave the way for a better understanding of how physical activity influences cardiac nerve function and could eventually inform treatments for conditions like arrhythmias and certain types of chest pain.