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Dad's Transplant Hope for Son
21 Apr
Summary
- New father Sam Vanderpump needs a liver transplant.
- Sam was diagnosed with liver disease at age four.
- A documentary highlights Sam's search for a donor.

Sam Vanderpump, a father of a two-month-old son named Duke, is in urgent need of a liver transplant. He was diagnosed with congenital hepatic fibrosis at the age of four, a condition that had remained dormant for 23 years before rapidly progressing to end-stage liver disease following a severe infection in December 2024. This progression necessitates a transplant to save his life and allow him to see his son grow.
Sam's mother, Simone, 56, volunteered as a living donor, but an anomaly at the final testing stage ruled her out, leaving her devastated. This experience, along with Sam's initial reluctance to have loved ones undergo the risky procedure, is detailed in an upcoming Channel 4 documentary. His wife, Alice, played a pivotal role in convincing him to explore living donor options for the sake of their family.
Doctors have assured Sam that living donor transplants in the UK have a minimal risk, with no recorded fatalities. Friends and family, including Made in Chelsea co-star Gareth Locke-Locke and older brother Jack, are undergoing testing. Sam remains on the transplant waiting list, managing his health while focusing on being present for his son, Duke.