Weight Regain Shock: Jabs Fail Long-Term?

New research indicates that the majority of individuals using weight loss injections like Mounjaro experience significant weight regain after cessation. An international trial found that 82% of participants regained at least a quarter of their lost weight within a year of stopping the medication, despite maintaining reduced-calorie diets and increased physical activity.

The study, published in JAMA Internal Medicine, also highlighted that this weight rebound correlates with a decline in health benefits, including worsened cholesterol levels and fasting insulin. Increased blood pressure was also noted, elevating the risk of stroke among those who regained weight.

These findings underscore the ongoing challenge of obesity management, suggesting that continuous treatment may be necessary. With millions in Britain using such injections, this research raises important questions about the long-term efficacy and implications of these popular weight loss medications.