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Brain Shrinkage Risk? Expert Warns on Extreme Dieting
1 Oct
Summary
- Chronic under-eating can deplete essential brain nutrients like omega-3s.
- The brain's structural integrity follows energy availability on a curve.
- Resistance training and neuro-nutrients protect brain health during weight loss.

Neuroscientist Dr. Tommy Wood warns that severe caloric restriction, often associated with popular weight-loss medications, can pose risks to brain health. He explains that the brain, being the most energy-demanding organ, relies on a consistent fuel supply. When energy availability drops too low, the brain may reduce in size by consuming its own tissue, a phenomenon observed in extreme endurance athletes during marathons.
While these medications can offer cognitive benefits by improving blood sugar control, chronic under-eating can lead to deficiencies in crucial nutrients such as omega-3 fats, iron, and protein. To safeguard cognitive function during weight loss, Wood advises incorporating resistance training at least twice weekly to maintain muscle mass and stimulate brain growth factors. Ensuring adequate intake of essential neuro-nutrients, including B vitamins, vitamin D, and iron, is also vital for preventing long-term cognitive impairment.