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Home / Health / Weight-Loss Drug Sparks Suicidal Depression Fears

Weight-Loss Drug Sparks Suicidal Depression Fears

23 Jan

•

Summary

  • Bunnie XO reported severe suicidal depression from retatrutide.
  • The drug is an investigational molecule not FDA approved.
  • Lilly warns against using unapproved versions of the drug.
Weight-Loss Drug Sparks Suicidal Depression Fears

Bunnie XO, wife of country singer Jelly Roll, has spoken out about a terrifying experience with the investigational weight-loss drug retatrutide. She reported suffering from severe suicidal depression, which she described as the worst she had experienced since 2020, after taking the drug obtained from a Nashville wellness center. Despite experiencing initial weight loss, the mental health side effects were so profound that she felt a complete lack of emotion and joy.

Lilly, the pharmaceutical company developing retatrutide, confirmed that the drug is an investigational molecule and is legally accessible only to participants in their clinical trials. They issued a strong warning against using any substance claiming to be retatrutide outside of these trials, clarifying that Bunnie's experience was not with a legitimate Lilly product. Experts, including Dr. Marc Siegel, have noted that retatrutide, a triple agonist, has potential links to depression and suicidal thoughts, similar to other GLP-1 drugs.

Retatrutide, nicknamed 'GLP-3,' targets three hormones and has shown significant weight loss in phase 3 trials, with participants losing an average of 71.8 lbs. Lilly anticipates further trial results in 2026 and potential FDA approval in 2027. The drug may also be explored for treating type 2 diabetes, kidney disease, and cardiovascular risks. However, potential side effects are similar to other GLP-1s, including nausea and rare reactions like pancreatitis, alongside the critical mental health concerns that require careful monitoring and immediate professional intervention if severe symptoms arise.

Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.
Retatrutide is an investigational weight-loss drug that targets three hormones. Side effects can include severe depression, suicidal thoughts, nausea, and other serious health issues.
Bunnie XO's severe reaction is a potential risk, and Lilly warns against using unapproved retatrutide outside of clinical trials, emphasizing that individual responses can vary greatly.
Retatrutide is legally available only to participants in Lilly's sponsored clinical trials and is not yet approved by the FDA for public use.

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