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Home / Health / Vitiligo Reversal: Mom's Legs Regain Color in Months

Vitiligo Reversal: Mom's Legs Regain Color in Months

23 Nov, 2025

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Summary

  • A mom's legs regained pigment after joining a Pfizer clinical trial.
  • The trial tests Ritlecitinib for treating nonsegmental vitiligo.
  • Her progress video gained nearly 7 million views online.
Vitiligo Reversal: Mom's Legs Regain Color in Months

A California mother has captivated millions online with a video documenting the significant repigmentation of her legs. Reshma Vincent, a small business owner from the Bay Area, participated in a clinical trial for vitiligo, a condition causing loss of skin pigment that she has had since age five.

Vincent's participation in a Pfizer study testing the oral medication Ritlecitinib for nonsegmental vitiligo has yielded remarkable results. A video she shared, showing her legs transforming from nearly entirely white in June to almost fully repigmented by November, has amassed millions of views and brought renewed hope to many.

This groundbreaking trial requires participants to pause other vitiligo treatments and are randomly assigned to either the drug or a placebo. Vincent expressed excitement about contributing to a trial that may offer a treatment option and inspire others facing similar skin conditions, while also reflecting on how vitiligo shaped her life and taught her strength.

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Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.
The California mom is part of a clinical trial testing Ritlecitinib, an oral medication for nonsegmental vitiligo.
In Reshma Vincent's case, her legs showed significant repigmentation within approximately five months during the clinical trial.
The article mentions Reshma Vincent is from the Bay Area, California, indicating a U.S.-based trial.

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