Home / Health / Vitiligo Reversal: Mom's Legs Regain Color in Months
Vitiligo Reversal: Mom's Legs Regain Color in Months
23 Nov
Summary
- A mom's legs regained pigment after joining a Pfizer clinical trial.
- The trial tests Ritlecitinib for treating nonsegmental vitiligo.
- Her progress video gained nearly 7 million views online.

A California mother has captivated millions online with a video documenting the significant repigmentation of her legs. Reshma Vincent, a small business owner from the Bay Area, participated in a clinical trial for vitiligo, a condition causing loss of skin pigment that she has had since age five.
Vincent's participation in a Pfizer study testing the oral medication Ritlecitinib for nonsegmental vitiligo has yielded remarkable results. A video she shared, showing her legs transforming from nearly entirely white in June to almost fully repigmented by November, has amassed millions of views and brought renewed hope to many.
This groundbreaking trial requires participants to pause other vitiligo treatments and are randomly assigned to either the drug or a placebo. Vincent expressed excitement about contributing to a trial that may offer a treatment option and inspire others facing similar skin conditions, while also reflecting on how vitiligo shaped her life and taught her strength.




