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Uterus-Sparing Surgery Outperforms Hysterectomy for Prolapse
21 Jul
Summary
- Hysteropexy with mesh shows a 36% lower risk of treatment failure after 10 years.
- The study involved 175 women across nine clinical sites in the U.S.
- Both surgical options improved patient-reported outcomes and sexual function.
A recent clinical trial indicates that women suffering from pelvic organ prolapse may achieve better long-term results with surgery that preserves their uterus. The study, published in JAMA Surgery, compared hysteropexy, which uses a mesh implant to support the uterus, against hysterectomy, the removal of the uterus.
After a decade of follow-up, women who had hysteropexy demonstrated a 36% reduced likelihood of treatment failure. This landmark research, conducted across nine U.S. clinical sites with 175 participants, suggests that preserving the uterus is a low-risk and effective option for patients.
Despite the initial advantages of hysteropexy, the study noted that the enhanced durability compared to native tissue procedures was not observed between years six and ten. However, both surgical methods provided sustained improvements in patient-reported outcomes and sexual function, with no significant differences detected between the groups.
The findings come as the U.S. Food and Drug Administration previously concluded in 2019 that there was insufficient data on transvaginal mesh efficacy, leading to the removal of certain mesh kits from the U.S. market, although they are still utilized globally.
