How does tattoo ink affect the immune system according to the new study?

The study found that tattoo ink accumulates in lymph nodes, causing chronic inflammation and altering immune responses.

Can tattoos affect vaccine responses like COVID-19?

Yes, researchers observed altered immune responses to vaccines, including a reduced response to the COVID-19 vaccine in mice.

Is the effect of tattoo ink on lymph nodes permanent?

Yes, the ink reportedly stays in the lymph nodes for a lifetime, even if the tattoo is removed.

Home / Health / Tattoo Ink Invades Lymph Nodes, Alters Immunity

Tattoo Ink Invades Lymph Nodes, Alters Immunity

7 Dec, 2025

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Summary

Tattoo ink accumulates in lymph nodes, impacting immune resistance.
The presence of ink caused chronic inflammation in mice lymph nodes.
Tattoos altered immune response to COVID-19 and influenza vaccines.

Tattoo Ink Invades Lymph Nodes, Alters Immunity

New research indicates that tattoos may lead to permanent alterations in the body's immune system and affect how vaccines work. Scientists observed that tattoo ink travels to and accumulates in lymph nodes, causing long-lasting inflammation and impacting immune cell function. This accumulation was linked to modified responses to specific vaccines, including a reduced reaction to the COVID-19 vaccine.

The study, which utilized mice, noted that the ink's presence in lymph nodes persisted for a lifetime, even if tattoos were removed. This raises concerns about the systemic toxic effects of insoluble pigments accumulating in the body, prompting calls for further investigation into tattoo ink safety.

With tattooing being a widespread practice globally, these findings are crucial for informing the public, policymakers, and regulatory bodies about potential health risks. Recent research also highlights a potential increased risk of lymphoma for individuals with extensive tattoos.