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Retinal Vessels Reveal Heart Health Secrets
15 Nov
Summary
- Retinal blood vessels can signal heart disease, lifespan, and aging
- Simpler retinal vessels linked to higher inflammation, heart disease risk
- Specific genes and proteins influence retinal vessel complexity and health

According to a study published in October 2025, the structure of a person's retinal blood vessels may provide valuable insights into their heart health and overall longevity. Researchers analyzed retinal imaging and genetic data from over 74,000 individuals and found that those with a "simpler" or less branched retinal microvasculature tend to have higher levels of inflammation, increased risk of heart disease and stroke, and shorter lifespans.
In contrast, people with more complex, tree-like retinal blood vessels are more likely to live longer and have healthier cardiovascular systems. The study identified specific genes and blood proteins, such as MMP12 and IgG-Fc receptor IIb, that contribute to this relationship by influencing age-related inflammation.
Experts explain that the retina's blood vessels reflect the health of the body's overall circulatory system, making them a valuable diagnostic tool. Dilated eye exams can provide a non-invasive way for doctors to examine these vessels and potentially detect early signs of conditions like diabetes, hypertension, and other cardiovascular diseases. By monitoring changes in the retinal microvasculature over time, healthcare providers can gain valuable insights into a patient's health and take preventative measures accordingly.


