EEG Scans May Predict Antidepressant Sexual Issues

Scientists have discovered a way to identify individuals prone to sexual dysfunction while taking antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs). A study involving 90 participants diagnosed with major depressive disorder found a correlation between higher brain serotonin levels and an increased likelihood of experiencing sexual side effects. These effects, which include decreased desire and difficulty achieving orgasm, were noted in a significant percentage of patients, impacting their quality of life. The researchers utilized electroencephalogram (EEG) brain scans to measure serotonin levels before participants began an eight-week course of escitalopram. This new approach could help clinicians better predict and manage potential sexual side effects before prescribing SSRIs. The study also noted limitations, including a female-skewed participant group and differences in sexual dysfunction prevalence between genders prior to treatment. Concerns regarding Post-SSRI Sexual Dysfunction (PSSD), a debated condition, have also been highlighted in recent years, with growing evidence suggesting its existence despite limited research.