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Poo Transplants Could Boost Fertility, Study Finds
3 Mar
Summary
- Gut bacteria transplants improved ovarian function in mice.
- Transplants from older mice unexpectedly boosted fertility.
- Microbiome links to ovarian health and reproductive aging.

Researchers have discovered that fecal microbiota transplants (FMT), commonly known as poo transplants, could potentially rejuvenate ovaries and enhance fertility. This groundbreaking study, conducted on mice at the USC Leonard Davis School of Gerontology, revealed a significant link between the gut microbiome and ovarian health. In the experiment, mice that received gut bacteria transplants after antibiotic treatment exhibited improved ovarian function and increased fertility.
Interestingly, the study found that transplants from older mice, whose own reproductive systems were declining, actually boosted the fertility of younger recipient mice. This challenges previous assumptions and suggests a complex, bidirectional communication between the gut and the ovaries. Scientists theorize that specific gut microbes, particularly those involved in estrogen metabolism, may compensate for age-related ovarian changes by producing more signaling molecules.
These findings, published in Nature Ageing, suggest that manipulating the gut microbiome could influence reproductive aging and potentially delay menopause. Such advancements could lead to longer, healthier lives for women by mitigating the negative health effects associated with menopause, including increased risks of osteoporosis, diabetes, heart disease, and dementia. FMT is currently being explored for various other health conditions and treatments.