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Insulin Resistance: The Hidden PMOS Driver
6 Sep
Summary
- Insulin resistance affects 65-70% of women with PMOS.
- Metabolic dysfunction in PMOS is independent of body weight.
- Lifestyle changes can significantly improve insulin sensitivity.
Polycystic ovary syndrome (PCOS) has been renamed polyendocrine metabolic ovarian syndrome (PMOS) to emphasize its foundation in metabolic health rather than solely gynecological symptoms. Insulin resistance, a condition where cells resist insulin's effects, is a primary driver for many PMOS manifestations.
This metabolic dysfunction affects an estimated 65% to 70% of women diagnosed with PMOS. Notably, it impacts individuals regardless of their body mass index, with up to 25% of lean individuals experiencing significant insulin resistance. Unmanaged, chronic insulin resistance increases risks for prediabetes, type 2 diabetes, fatty liver disease, and cardiovascular issues.
Improving insulin sensitivity involves a holistic lifestyle approach. Prioritizing protein and fiber, consistent exercise, minimizing refined sugars, and optimizing sleep and stress levels are key strategies. These lifestyle measures, potentially combined with medication, can help stabilize blood glucose and restore hormonal balance, thus protecting reproductive and long-term health.
