Pharmacists Warn: Avoid These Holiday Treats if Taking Certain Drugs

With Christmas just around the corner on November 13, 2025, health experts are warning patients on prescription medications to be cautious about their holiday food and drink choices. Pharmacists Amir Bhogal and Deborah Grayson have identified several seasonal items that can interfere with common drugs.

Grapefruit, both the fresh fruit and juice, can affect the liver enzymes responsible for breaking down many medications, causing the drugs to build up to unsafe levels in the bloodstream. This poses risks for those taking cholesterol-lowering statins, blood pressure medicines, antidepressants, and immunosuppressants.

Leafy greens like spinach, kale, and Brussels sprouts are rich in vitamin K, which can disrupt the blood-thinning effects of warfarin. Patients on this medication need to maintain a consistent intake of these foods.

Dairy products can also be problematic, as the calcium they contain can reduce the absorption of certain antibiotics used to treat chest and urinary tract infections. Spacing out medication and dairy intake by at least two hours is recommended.

Additionally, tyramine-rich foods like aged cheeses, cured meats, and soy products can dangerously interact with depression and anxiety medications, potentially causing a sudden spike in blood pressure. Alcohol, too, can have unpredictable and dangerous effects when combined with many drug classes.