What is the new oral Wegovy pill approved for?

The new oral Wegovy pill is approved for weight loss in adults who are overweight or obese and have at least one weight-related condition.

When will the Wegovy pill be available in the US?

The Wegovy pill is expected to launch in the U.S. in early January 2026.

How effective is the oral Wegovy medication?

Clinical trials showed the oral Wegovy pill achieved an average weight loss of 16.6%, similar to the injectable version.

Home / Health / Oral Wegovy Approved: Weight Loss Revolution!

Oral Wegovy Approved: Weight Loss Revolution!

24 Dec, 2025

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Summary

First-ever oral GLP-1 medication for weight loss approved.
Wegovy pill shows 16.6% average weight loss in trials.
Oral version offers similar results to injectable Wegovy.

Oral Wegovy Approved: Weight Loss Revolution!

The U.S. has approved the first-ever oral GLP-1 medication for weight loss, marking a significant advancement in obesity treatment. The once-daily semaglutide pill, branded as Wegovy, aims to help individuals reduce excess body weight and lower cardiovascular risk.

Clinical trials, including the OASIS 4 program, revealed that the Wegovy pill resulted in an average weight loss of 16.6% for obese or overweight adults with comorbidities. A notable one in three participants achieved 20% or greater weight reduction, mirroring the efficacy of the injectable Wegovy with a similar safety profile.

This convenient oral option is slated for a U.S. launch in early January 2026, with further regulatory submissions in Europe and other regions. While promising, experts note potential variations in gastrointestinal absorption and compare its effectiveness to other drugs like tirzepatide, emphasizing the importance of lifestyle habits for sustained results.