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Young Indians: Genes vs. Lifestyle in Obesity Battle
28 Feb
Summary
- Younger Indians with genetic obesity risk face greater danger.
- Lifestyle interventions show best results below age 50.
- Indian obesity guidelines need revision for local body patterns.

Younger individuals in India under 50 with a high genetic predisposition to obesity face significantly greater risks influenced by their daily dietary habits and lifestyle choices. A recent study, a collaboration between AIG Hospitals and universities in Luxembourg and Germany, found that these factors combined pose a more substantial threat than in older adults.
This research underscores the critical role of lifestyle interventions, which are most effective in younger populations. Doctors observed that healthy changes aid in building muscle and reducing fat more readily before the age of 50. After 60, age-related changes make reversing obesity risks more challenging.
The study analyzed genetic data from over 6,600 Indians in the UK and a smaller Indian cohort. Its findings are particularly relevant as India faces a surge in metabolic diseases like diabetes and fatty liver, with obesity being a major contributor.
Experts advocate for revising India-specific obesity guidelines to account for the tendency of Indians to develop abdominal obesity, which increases metabolic risk even at lower body weights. Early metabolic screening, focusing on waist size and belly fat, alongside promoting healthy lifestyles from early adulthood, is crucial for prevention.




