What is the new nasal spray vaccine for whooping cough called?

The new nasal spray vaccine undergoing trials is called BPZE1.

How does the new BPZE1 vaccine differ from the current whooping cough vaccine?

The current vaccine protects infants but doesn't stop transmission, while BPZE1 aims to prevent bacteria colonization and halt the spread.

When was the last major whooping cough outbreak in Britain?

Britain experienced its worst whooping cough outbreak in 40 years last year (2024).

Home / Health / New Nasal Spray Vaccine Could End Whooping Cough Spread

New Nasal Spray Vaccine Could End Whooping Cough Spread

3 Dec, 2025

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Summary

A new nasal spray vaccine, BPZE1, is being trialed to stop whooping cough spread.
The current injectable vaccine protects infants but doesn't stop transmission.
The trial vaccine BPZE1 has shown promise in preventing bacteria colonization.

New Nasal Spray Vaccine Could End Whooping Cough Spread

A novel nasal spray vaccine, BPZE1, is currently undergoing trials in the UK, offering a potential new weapon against the dangerous bacterial infection whooping cough. This innovative vaccine aims to prevent the transmission of the bacteria, a feat not achieved by the existing injectable vaccine offered to pregnant women. The current vaccine effectively transfers immunity to newborns, providing up to 91% protection against infant death, but does not halt the spread.

The new trial, backed by the National Institute for Health and Care Research, has shown promising results. It is the first time a whooping cough vaccine has demonstrated the ability to prevent the bacteria from colonizing the upper respiratory tract in humans. If further trials confirm these findings and the vaccine receives approval, it could significantly alter public health strategies against this highly infectious disease.