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Mom Battles Aggressive Brain Cancer After Losing 3 Kids
6 Jan
Summary
- Lori Coble diagnosed with stage 4 glioblastoma brain cancer in July 2025.
- She lost her three young children in a tragic car accident in May 2007.
- Lori has undergone multiple surgeries and treatments for her aggressive cancer.
Lori Coble, who lost her three children in a freeway crash in May 2007, is now facing a new devastating challenge. In July 2025, she was diagnosed with stage 4 glioblastoma, an aggressive brain cancer. This diagnosis came after years of grieving and raising triplets conceived via IVF to honor her lost children.
Doctors initially gave Lori a grim prognosis, estimating only a few months to live without treatment. She has since undergone multiple complex surgeries to resect the rapidly growing tumor, facing significant complications including a stroke and loss of motor control. Her husband, Chris, has taken an unpaid leave of absence to provide round-the-clock care.
Despite numerous setbacks and Lori's directive for no more surgeries, her family continues to support her fight. They have established a home 'mini-hospital' and a GoFundMe to manage the substantial costs of her ongoing care. Lori's resilience in the face of such profound tragedy continues to inspire.




