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Mid-life Nerves? Dementia Risk May Be Near
16 Dec
Summary
- Specific depressive symptoms in mid-life predict higher dementia risk.
- Over 5,000 adults over 55 tracked for over two decades.
- Early symptom identification could enable lifestyle changes.

Experts suggest that mid-life bouts of nervousness or concentration difficulties could serve as early indicators for dementia. Research involving over 5,000 adults aged 55 and above, followed for more than two decades, revealed a correlation between clusters of specific depressive symptoms and a higher likelihood of developing dementia later in life.
The study identified six key warning signs, including worsening anxiety, difficulty concentrating, and a loss of self-confidence. Those exhibiting five or more of these symptoms showed a significantly increased risk. This symptom-level approach, published in The Lancet Psychiatry, may offer doctors a method to identify at-risk individuals years before cognitive decline becomes apparent.
While the connection between depression and dementia is complex, this research provides insights into specific mental health markers. Early detection could pave the way for encouraging lifestyle modifications to potentially delay dementia's progression, a condition that currently has no cure and affects nearly one million people in the UK.




