What is methylene blue and why are biohackers using it?

Methylene blue is a compound with historical uses as a dye and medication. Biohackers promote it for alleged wellness benefits like enhanced energy and cognition.

Is methylene blue safe for cognitive enhancement?

Human studies are preliminary. Experts warn of risks like serotonin toxicity and lack of supplement oversight, advising consultation with a clinician.

Can methylene blue interact with my medications?

Yes, methylene blue can cause dangerous serotonin toxicity, especially if you take certain antidepressants like Zoloft or Lexapro.

Home / Health / Methylene Blue: From Dye to Dangerous Biohack?

Methylene Blue: From Dye to Dangerous Biohack?

15 Dec, 2025

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Summary

Online influencers promote methylene blue for alleged wellness benefits.
Early research shows potential cellular energy benefits in lab studies.
Serious risks include serotonin toxicity and genetic disorder dangers.

Methylene Blue: From Dye to Dangerous Biohack?

Methylene blue, a compound with a history as a textile dye and medical treatment, is now being promoted by online influencers and biohackers for purported wellness benefits. Proponents claim it enhances mitochondrial function, leading to advantages like slower aging, improved mood, and sharper cognition, with some even suggesting it alleviates jet lag.

Scientific evidence supporting these claims is still developing. While lab and animal studies indicate methylene blue may help cells produce energy more efficiently and offer neuroprotective effects, human trials are limited and preliminary. Experts like Lorne Hofseth caution that risks currently overshadow benefits for supplement users, despite promising research on modified forms for Alzheimer's treatment.