Home / Health / Pharmacist Warns: Common Painkillers Harmful with Metformin
Pharmacist Warns: Common Painkillers Harmful with Metformin
7 Nov
Summary
- Pharmacist warns against combining Metformin with common painkillers.
- Painkillers like Ibuprofen can strain kidneys, affecting Metformin removal.
- Vitamin B12 deficiency is a common, serious side effect of long-term Metformin use.

Pharmacist Raj Patel has issued a critical warning to over 3 million individuals in the UK who take Metformin, a widely used medication for type-2 diabetes. He highlights that combining Metformin with common over-the-counter pain relievers, like Ibuprofen and Diclofenac, poses a risk to kidney function. These anti-inflammatory drugs can place extra strain on the kidneys, which are responsible for removing Metformin from the body. Dehydration can exacerbate this risk.
Other medications, including certain water tablets and blood pressure medicines, can also affect kidney function and require monitoring when taken with Metformin. Excessive alcohol consumption is another concern, potentially increasing the risk of a rare but serious condition called lactic acidosis, particularly when dehydrated or fasting.
Beyond drug interactions, long-term Metformin use, which is generally safe and has no time limit, is associated with a common side effect: Vitamin B12 deficiency. Pharmacist Anil Sharma emphasizes the importance of monitoring B12 levels, as deficiency can lead to nerve damage, anemia, memory loss, and confusion.
Individuals experiencing symptoms of B12 deficiency should consult a GP, as prompt diagnosis and treatment are crucial. Untreated deficiency can result in irreversible nerve damage. Patients are strongly advised to consult their pharmacist about suitability with Metformin before starting any new medication, vitamin, or supplement, and never to stop prescribed medicines independently.