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Bialik: GLP-1 Drug Caused 3-Day Medical Ordeal
7 Jun
Summary
- Bialik experienced severe cramping, bloating, and flu-like aches.
- She suffered explosive diarrhea and inability to keep down water.
- Doctors later advised the drug was inappropriate for her condition.

Mayim Bialik has detailed a harrowing experience with a GLP-1 weight-loss medication, calling it a "nightmare." After a single injection, the actress suffered intense side effects for three days. These included severe cramping, bloating, full-body aches akin to the flu, and explosive diarrhea, leaving her unable to retain even small sips of water.
Bialik's ordeal was compounded by debilitating sulfur burps and repeated sneezing fits. She revealed that her decision to try the drug was prompted by doctors suggesting it might help with her autoimmune conditions, not for weight loss. However, a gastroenterologist later advised that GLP-1 drugs are only suitable for life-compromising obesity and that Bialik did not meet this specific medical bar.
Despite the adverse reaction, Bialik noted a subtle physical change after discontinuing the medication. Other celebrities, like Kris Jenner and Amy Schumer, have also shared negative experiences with similar drugs.