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Elephantiasis: Millions Suffer Tropical Disease
23 Jun
Summary
- Lymphatic filariasis, or elephantiasis, affects millions globally.
- Parasites spread by mosquitoes damage the lymphatic system.
- Mass drug administration has controlled the disease since 2000.

Lymphatic filariasis, or elephantiasis, is a significant global health concern, impacting millions across Asia, Africa, the Pacific, and the Americas. This neglected tropical disease is caused by parasites transmitted through mosquito bites, which inhabit and damage the human lymphatic system. The resulting chronic swelling can lead to severe disfigurement and permanent disability.
Since 2000, the World Health Organization has led a global program to eliminate lymphatic filariasis. Mass drug administration, involving annual treatments with drugs like albendazole, DEC, or ivermectin, has been instrumental in interrupting transmission. This strategy has proven highly effective, reducing infections by 74% between 2000 and 2018. Twenty-one countries have since been declared free of the disease.
While initial infections can be treated with diethylcarbamazine, chronic symptoms like elephantiasis require ongoing management. This includes swelling control, diligent skin care to prevent secondary infections, and sometimes surgery for conditions like scrotal swelling. Other prevention methods include mosquito control through bed nets and insecticide spraying.