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Low T? Expert Shares Personal Journey
26 Feb
Summary
- Longevity researcher experienced classic low testosterone symptoms in his early 50s.
- Initial total testosterone tests were inconclusive, leading to further investigation.
- Weekly testosterone injections ultimately resolved symptoms and improved well-being.

In his early 50s, longevity researcher Matt Kaeberlein began experiencing hallmark symptoms of low testosterone, including fatigue, reduced libido, and difficulty with body composition changes despite diligent exercise and diet. His initial "total testosterone" blood test yielded results considered "low-normal," leading his doctor to deem hormone replacement therapy unnecessary.
However, further investigation using a "free testosterone" test revealed "primary hypogonadism," a condition where the testes do not produce sufficient testosterone. This prompted Kaeberlein to seek medical advice from a specialist experienced in testosterone therapy. He eventually opted for weekly testosterone injections after finding other methods, like supplements and oral medication, less effective or carrying side effects.
Kaeberlein notes that TRT can face stigma due to perceptions of 'natural' being superior and its misuse by younger individuals. He emphasizes that while TRT can significantly benefit middle-aged individuals experiencing testosterone decline, it is not a standalone solution for muscle gain and requires consistent exercise and nutrition. He also highlights the potential impact on fertility, a consideration for younger men.




