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Lost Smell for 15 Years? New Hope Emerges
1 Mar
Summary
- Chronic rhinosinusitis caused a 15-year loss of smell for one patient.
- Nasal polyps and severe inflammation are key causes of smell loss.
- New treatment dupilumab offers hope for severe, resistant cases.

For 15 years, Alison Cavanagh experienced a profound loss of smell and taste, a consequence of chronic rhinosinusitis and nasal polyps. This condition significantly impacted her daily life, diminishing her enjoyment of food and social activities. Experts emphasize that early intervention for sinusitis is vital to prevent symptoms from becoming severe and long-term. Sinusitis, a common infection, can become chronic in 5-10% of Britons, leading to debilitating issues like headaches and persistent congestion.
Nasal polyps, fleshy growths, can block olfactory nerves, causing smell and taste impairment. Research indicates a genetic predisposition for chronic rhinosinusitis, often linked to other inflammatory airway conditions like asthma. While saline nasal rinsing and steroid sprays are common treatments, they are not always effective. For those unresponsive to conventional therapies, a new twice-weekly injection treatment, dupilumab, has been approved by the NHS, targeting underlying inflammation and offering a transformative solution for severe cases.