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Lassa Fever: The Deadly Ebola-Like Threat Imported to US
5 Mar
Summary
- Lassa fever, an Ebola-like illness, poses an unrecognized global threat.
- Imported cases of the disease have already been detected in the US.
- Early detection and treatment are vital to prevent fatalities from Lassa fever.

Lassa fever, a severe illness originating in West Africa, is emerging as a significant global threat, with cases already documented in the United States. This disease, primarily spread by rodents but also transmissible between humans, claims thousands of lives each year, particularly in Nigeria, Liberia, and Sierra Leone.
The World Health Organization has identified Lassa fever as a critical pandemic risk. Globally, over 32 imported cases have been recorded, including within the U.S., with a concerning one-third fatality rate among these imported cases.
Researchers emphasize the urgent need for enhanced detection and treatment strategies. Limited testing availability, even in endemic regions, leads to many undiagnosed cases. Symptoms range from mild fever and headaches to severe complications like breathing difficulties and bleeding, with pregnant women facing heightened risks.
The PREPARE study highlighted that 11 percent of patients admitted with fever, even without initial suspicion, were found to have Lassa fever. Children aged 5 to 17 were disproportionately affected. Missed diagnoses not only worsen patient outcomes but also increase exposure risks for healthcare workers and facilitate further human-to-human transmission.
Experts stress that early detection is key to preventing deaths, offering a narrow window for effective intervention. Improving access to diagnostics and supportive care can significantly reduce mortality and prevent the pathogen from spreading further.




