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Home / Health / Poor Kidneys Double Dementia Risk for Some

Poor Kidneys Double Dementia Risk for Some

5 Dec, 2025

•

Summary

  • Kidney disease nearly doubles dementia risk in vulnerable individuals.
  • Poor kidney function accelerates dementia in those with brain biomarkers.
  • Doctors should consider kidney health when interpreting Alzheimer's biomarkers.
Poor Kidneys Double Dementia Risk for Some

A recent study has uncovered a concerning connection between kidney health and dementia risk. Researchers found that individuals with impaired kidney function who also show early biological markers for neurodegeneration face a significantly higher likelihood of developing dementia. Specifically, for those with elevated proteins linked to Alzheimer's in their blood, poor kidney health nearly doubles their risk, acting as a potent accelerator of the disease process.

The findings emphasize that kidney function plays a crucial role in modulating dementia risk, even in the absence of strong genetic predispositions. When kidneys fail, toxins and inflammatory substances accumulate in the blood, potentially damaging brain cells. Scientists suggest this toxic environment may spur on dementia in vulnerable individuals, necessitating a holistic approach to patient assessment.

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These discoveries, published in the journal Neurology, underscore the importance of considering kidney health when interpreting blood-based biomarkers for Alzheimer's disease. Monitoring kidney function may help clinicians better identify individuals at risk for faster dementia progression, leading to more targeted interventions and improved patient care strategies.

Disclaimer: This story has been auto-aggregated and auto-summarised by a computer program. This story has not been edited or created by the Feedzop team.
The Karolinska Institutet study found that poor kidney function nearly doubles dementia risk for individuals already showing early signs of neurodegeneration in their blood.
Failing kidneys may not filter toxins and inflammatory substances effectively, creating a harmful environment that can damage brain cells and spur dementia.
Yes, doctors should consider kidney health when interpreting Alzheimer's biomarkers in the blood, as it significantly impacts dementia risk and progression.

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