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Keto Diet May Reverse Type 2 Diabetes Better Than Low-Fat
24 Apr
Summary
- Keto diet may offer better diabetes reversal than low-fat.
- Study focused on proinsulin to C-peptide ratio for beta-cell function.
- Adherence and diet composition are key challenges for keto success.

A recent study published in the Journal of the Endocrine Society indicates that individuals with type 2 diabetes may experience better reversal outcomes by following a high-fat, low-carbohydrate ketogenic diet.
The 12-week study involved 51 adults aged 55-62 with type 2 diabetes, comparing a keto diet to a low-fat diet. Researchers monitored the proinsulin to C-peptide ratio, a marker for pancreatic beta-cell function.
Results showed that while both diets led to weight loss, the keto group exhibited a significant decrease in proinsulin secretion, correlating with improved beta-cell function. Elevated proinsulin suggests beta-cells are overwhelmed; a reduction indicates reduced stress and increased efficiency.
Scientists theorize that removing chronic glucose exposure on a keto diet may allow beta-cells to repair their secretory mechanisms. However, experts caution that adherence to the keto diet, which requires discipline and careful selection of fats and proteins, remains a significant challenge.
Dietitians emphasize that the sustainability, nutritional adequacy, and impact on overall health, particularly cardiovascular health, should be considered. While low-carb diets may offer short-term glycemic control, long-term effectiveness and potential side effects require further investigation and professional guidance.