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Innovative Immunotherapy Combo Approved for Advanced Womb Cancer
5 Aug
Summary
- New treatment combination approved for NHS use
- Reduces risk of death by 26% compared to chemo alone
- Offers hope and better quality of life for affected women

In a significant development, a new treatment combination has been approved for widespread use in the NHS in England to help women with an advanced form of womb cancer. As of 2025-08-06T00:44:56+00:00, the National Institute for Health and Care Excellence (NICE) has given the green light for the use of pembrolizumab, an immunotherapy drug, alongside chemotherapy drugs carboplatin and paclitaxel.
This innovative treatment approach is expected to benefit around 2,100 women each year who have been diagnosed with stage four endometrial cancer, a particularly aggressive form of the disease. Clinical trials have shown that the combination therapy can reduce the risk of death by 26% compared to chemotherapy alone. Additionally, the treatment can help slow down the progression of the cancer, offering patients a better quality of life.
Helen Knight, the director of medicines evaluation at NICE, has described this approval as a "major step forward" in the treatment of advanced endometrial cancer. The treatment will provide a powerful new option for those affected, giving them hope and the potential for improved outcomes. Experts have welcomed this development, stating that it will offer a better quality of life and better outcomes for women battling this devastating form of cancer.