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Heatstroke Kills Days After Cooling Down
11 Aug
Summary
- Heatstroke is fatal even after the body temperature returns to normal.
- The immune system can overreact to heat, causing organ damage.
- Older adults, babies, and those with chronic conditions are most at risk.

As the UK braces for extreme temperatures, a scientist has detailed the often-fatal nature of heatstroke. Heatstroke occurs when the body's core temperature exceeds 40°C, impairing brain function and causing muscles to break down. The danger, however, extends beyond direct heat damage.
Even after cooling, the immune system can be tricked into an overdrive response, potentially causing fatal kidney failure or brain damage hours or days later. This immune overreaction is a critical factor in heatstroke fatalities.
Certain groups are at higher risk, including the elderly, infants, and individuals with heart disease, diabetes, or obesity. Certain medications, alcohol, dehydration, and social isolation also increase susceptibility. Athletes and outdoor workers face risks from pushing their bodies beyond their cooling capacity.