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Fentanyl Users Develop Mind-Boggling Tolerance
15 Jun
Summary
- Users daily take fentanyl doses 60 times lethal amount for non-users.
- Average user consumes opioid doses equivalent to 9,000mg morphine.
- Extreme tolerance makes quitting fentanyl exceptionally difficult.
People who use illicit fentanyl build up a remarkable tolerance to the drug, regularly taking doses that would be fatal to others. Researchers found that the average fentanyl user in Los Angeles consumes a daily amount roughly 60 times the 2-milligram dose that could kill someone who has never used opioids.
This daily intake is equivalent to nearly 9,000 milligrams of morphine. Such high exposure levels make quitting fentanyl exceptionally difficult, as standard addiction medications are not designed to manage withdrawal from these massive doses. The synthetic nature of fentanyl and its high potency contribute to this challenging reality for users and treatment providers.