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Exercise Rewires Heart Nerves: A New Approach
1 Jan
Summary
- Exercise creates distinct left-right nerve changes in the heart.
- Right side nerve cells multiply; left side cells enlarge.
- Findings may improve targeted treatments for heart conditions.

New research from the University of Bristol indicates that regular aerobic exercise may fundamentally alter how the heart's nerves function. The study, conducted on lab rats, revealed a previously unrecognized pattern of distinct left-right adaptations in the nerve control system that regulates the heart.
Researchers observed that exercise led to a significant increase in nerve cells on the right side of the heart's nerve hub, while on the left side, existing nerve cells grew larger. This side-specific remodeling suggests a more complex neural response to physical activity than previously understood.
These early findings, published in Autonomic Neuroscience, could pave the way for more targeted and effective treatments for various cardiovascular conditions. Scientists believe understanding this hidden nerve asymmetry may eventually help doctors personalize therapies for patients unable to exercise or those whose symptoms persist.




