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Flu Surges Weeks Early in UK, Vaccine Struggles to Keep Up
14 Nov
Summary
- Flu season started a month earlier than usual in the UK
- New H3N2 flu strain has 7 mutations, reducing vaccine efficacy in adults
- Flu vaccine still highly effective in preventing severe illness in children

As of November 14th, 2025, the UK is experiencing an unusually early and severe flu season. Flu cases have spiked weeks ahead of the typical mid-November to mid-February timeframe, with 11% of daily tests already coming back positive for the influenza virus - a significant jump from just 3% at the same time last year.
The primary driver behind this early surge appears to be a new strain of the influenza A H3N2 virus, which has developed seven genetic mutations compared to previous strains. This high level of mutation has reduced the effectiveness of the current flu vaccine, especially for adults. While the vaccine remains highly protective for children, with 38% of positive tests coming from school-aged kids, its efficacy in adults has dropped to just 30-40%.
Experts warn that the combination of an earlier-than-usual start to flu season, the new mutated strain, and lower vaccine effectiveness could result in one of the UK's worst flu outbreaks in recent memory. Data from the southern hemisphere's recent flu season, which is often a harbinger of what's to come in the north, showed a 10% increase in cases compared to the previous year. With the flu's R-number also rising from the typical 1.2 to 1.4, the potential for a severe outbreak is high.
Despite these concerning trends, the article emphasizes that the flu vaccine remains the best form of protection, especially for children and those in close contact with vulnerable populations. Alongside vaccination, following standard flu guidance, isolating when symptomatic, and practicing good hygiene can all help mitigate the impact of this year's flu season.




