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Dementia Drugs Linked to Higher Death Risk
8 Mar
Summary
- Antidepressants and anti-anxiety medications may increase mortality risk in dementia patients.
- Study analyzed nearly 29,000 dementia patients in Northern Ireland over nine years.
- Medication reviews are crucial for dementia patients to ensure appropriateness and need.

A significant study originating from Queen's University Belfast indicates that certain antidepressants and anti-anxiety medications may elevate the risk of death for individuals living with dementia. This research, analyzing data from 28,781 dementia patients in Northern Ireland between 2012 and 2020, revealed concerning associations.
During the nine-year follow-up period, antidepressants were prescribed to 59.2% of those who died, while anti-anxiety medications were given to 44.8%. The study found a slight increase in death risk with antidepressants and a marked increase with anti-anxiety drugs.
Researchers emphasize that dementia, a leading global cause of death with no current cure, affects millions worldwide. Given that people with dementia often have multiple medical conditions requiring various medications, the appropriateness of these prescriptions is paramount. The study highlights the vital role of regular and thorough medication reviews by healthcare professionals, such as GPs and pharmacists, to ensure ongoing suitability and necessity of treatments for dementia patients.