Home / Health / Actor's Story Sparks Awareness of Rare CCD
Actor's Story Sparks Awareness of Rare CCD
23 Dec
Summary
- Cleidocranial Dysplasia affects bone and dental development.
- It's a rare genetic disorder, estimated at 1-9 cases per million.
- Management focuses on symptoms, with no known cure.
Actor Gaten Matarazzo's openness about living with Cleidocranial Dysplasia (CCD) has significantly boosted public awareness of this rare genetic disorder. CCD primarily affects bone and dental development, stemming from mutations in the RUNX2 gene, which is crucial for bone formation. The condition can lead to underdeveloped collarbones and delayed skull bone closure, but dental abnormalities are often the most pronounced features, including delayed tooth loss and eruption issues.
Globally, CCD is rare, with prevalence estimates around 1-9 cases per million. In India, specific data is scarce, and underdiagnosis is likely due to limited access to specialized care. Clinical features vary widely, from subtle signs to significant skeletal and dental challenges requiring long-term management.
Diagnosis typically involves clinical examination and imaging, with genetic testing offering confirmation. There is no cure for CCD; treatment focuses on managing its manifestations. With comprehensive, multidisciplinary care, individuals with CCD can lead full lives, and increased visibility from public figures like Matarazzo aids in understanding and destigmatizing the condition.
