What did the JAMA review find about medical cannabis?

The JAMA review found weak or inconclusive evidence for most health reasons people use medical cannabis and noted nearly 30% of patients develop use disorder.

Do doctors understand medical cannabis according to the study?

No, a 2021 review cited found only 33% of clinicians globally were confident in their knowledge of medical cannabis, needing more education.

What are the risks of medical cannabis use based on the JAMA review?

Risks include potential contamination, exposure to toxins if inhaled, and exacerbation of mental health issues, alongside a high rate of cannabis use disorder.

Home / Health / Cannabis: Hype vs. Health Reality

Cannabis: Hype vs. Health Reality

12 Dec, 2025

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Summary

Medical cannabis research often shows weak or inconclusive evidence.
Nearly 30% of medical cannabis patients show signs of disorder.
Doctors lack confidence and knowledge regarding medical cannabis.

A comprehensive review of 15 years of research reveals a significant disconnect between the public's reasons for using cannabis and the scientific evidence supporting its benefits. Millions of Americans turn to cannabis for pain, anxiety, and sleep issues, yet studies indicate the evidence for effectiveness is frequently weak or inconclusive.

The analysis also highlighted that almost 30 percent of individuals using medical cannabis meet the criteria for cannabis use disorder. Compounding this, a notable number of clinicians express uncertainty and a need for further education regarding medical cannabis, indicating a knowledge gap within the medical community.

Despite the growing $32 billion cannabis industry and increasing public acceptance, researchers emphasize the need for rigorous clinical trials. Concerns remain about product quality control, potential contamination, and the risk of adverse effects, particularly for conditions like chronic pain and anxiety where evidence is still developing.