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Tick Bite Allergy Impacts Hundreds of Thousands
18 Jul
Summary
- Hundreds of thousands affected by tick-borne alpha-gal syndrome.
- Legislation seeks to label alpha-gal as a major allergen.
- Medications and medical products may contain hidden allergens.

An estimated half a million Americans are affected by alpha-gal syndrome (AGS), a condition caused by a lone star tick bite. This allergy can trigger reactions to mammal products, including those found in food, medications, and medical equipment. Advocates are lobbying for legislative action to address the challenges faced by those with AGS.
Two key bills are progressing in Congress. One, the Alpha-gal Allergen Inclusion Act, would require food manufacturers to label the alpha-gal molecule, similar to other major allergens. A separate bill proposes mandating that manufacturers disclose ingredients in prescription medications that contain major food allergens.
Living with AGS often means constant vigilance, as hidden animal-derived ingredients can be present in food products under vague labels like 'natural flavorings' or in medications, such as gelatin capsules or lactose fillers. These ingredients can cause severe reactions, including anaphylaxis, for a significant portion of AGS patients.
AGS reactions can vary widely, making diagnosis and management complex. While some states have begun requiring mandatory reporting of AGS cases, further research is needed to understand the allergy and its severe reactions. Funding cuts to medical research pose a concern for advancing understanding and finding solutions for this condition.