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Musi River: Hotspot for 'ISIS Drug' and Superbugs
3 Aug
Summary
- Musi River shows highest concentrations of Tramadol and other pharmaceuticals.
- Study warns of superbug creation due to drug contamination in rivers.
- Caffeine detected in all rivers indicates widespread sewage discharge.

A new study analyzing seven major Indian river systems has revealed alarming levels of pharmaceutical contamination, particularly in the Musi River. This river system has emerged as a significant hotspot, showing the highest concentrations of drugs such as Tramadol, often dubbed the 'ISIS drug.' The research, published recently, warns that the accumulation of antibiotics in these waterways could create breeding grounds for antimicrobial resistance, posing a serious public health risk.
Researchers found that urban river stretches, including the Musi in Hyderabad, are heavily polluted due to direct discharge of untreated domestic sewage and industrial effluents. Caffeine was detected in all samples, underscoring the widespread issue of sewage contamination. Besides Tramadol, analgesics like acetaminophen and hypertension medications were also found in high concentrations.
The study highlights Hyderabad's role as a pharmaceutical hub, with potential contamination linked to manufacturing and distribution facilities. The Musi alone is estimated to carry substantial annual loads of various pharmaceutical residues towards the Krishna River and the Bay of Bengal. The lower stretch of the Musi has been flagged for the highest potential for antimicrobial resistance development.
While groundwater contamination was detected, the risk to human health through drinking water was deemed low. However, the ecological risk to aquatic life, especially fish, from certain drugs like Telmisartan was assessed as very high. The study calls for urgent policy interventions, including improved sewage treatment and monitoring of industrial effluents, to address pollution in critical riverine systems.